Karin Enander

Karin Enander

Associate professor

Dr. Karin Enander obtained a MSc in Molecular Biotechnology from Uppsala university in 1999 and a PhD in Chemistry from Linköping university in 2003. After postdoctoral studies at Uppsala University and Université Louis Pasteur Strasbourg in 2004-2005, she joined professor Bo Liedbergs group at Linköping university. In 2011, she became a docent (associate professor) at Linköping university and obtained a position as a senior lecturer.

Research interest

My research is focused on design and interaction analysis of peptides and proteins, mainly for sensing and bioassay purposes but also in a more fundamental context. My experience also involves biosensor surface design and immobilization chemistry.

Expertise in

  • Peptides
  • Biomolecular interaction analysis
  • Surface plasmon resonance 
  • Fluorescence spectroscopy

Education

MSc in Molecular Biotechnology

Uppsala University, Uppsala, Sweden

PhD in Chemistry

Linköping University, Linköping, Sweden

Selected publications

Peer-reviewed articles

Halling Linder C, Enander K, and Magnusson P: "Glycation contributes to interaction between human bone alkaline phosphatase and collagen type I", Calcified Tissue International, 2016, 98:284–293.

Petrone L, Aldred N, Emami K, Enander K, Ederth T, and Clare AS: "Chemistry-specific surface adsorption of the barnacle settlement-inducing protein complex", Interface Focus, 2015, 5:20140047.

Selegård R, Enander K, and Aili D: "Generic phosphatase activity detection using zinc mediated aggregation modulation of polypeptide-modified gold nanoparticles", Nanoscale, 2014, 6:14204-14212.

Ericsson EM, Enander K, Bui L, Lundström I, Konradsson P, and Liedberg B: "Site-specific and covalent attachment of His-tagged proteins by chelation assisted photoimmobilization: A strategy for microarraying of protein ligands", Langmuir, 2013, 29:11687-11694.

Kanmert D, Brorsson A-C, Jonsson B-H, and Enander K: "Thermal induction of an alternatively folded state in human IgG-Fc.", Biochemistry, 2011, 50:981-988.

Choulier L and Enander K: "Environmentally sensitive fluorescent sensors based on synthetic peptides.", Sensors, 2010, 10: 3126-3144.

Kanmert D, Enocsson H, Wetterö J, Kastbom A, Skogh T, and Enander K: "Designed surface with tunable IgG density as an in vitro model for immune complex mediated stimulation of leukocytes.", Langmuir, 2010, 26:3493–3497.

Andersson O, Nikkinen H, Kanmert D, and Enander K: "A multiple-ligand approach to extending the dynamic range of analyte quantification in protein microarrays. ", Biosensors and Bioelectronics, 2009, 24:2458-2464.

Carlsson J, Gullstrand C, Westermark G, Ludvigsson J, Enander K, and Liedberg B: "An indirect competitive immunoassay for insulin autoantibodies based on surface plasmon resonance.", Biosensors and Bioelectronics, 2008, 24:882-887.

Enander K, Choulier L, Olsson L, Yushchenko D, Kanmert D, Klymchenko A, Demchenko A, Mély Y, and Altschuh D: "A peptide-based, ratiometric biosensor construct for direct fluorescence detection of a protein analyte.", Bioconjugate Chemistry, 2008, 19:1864-1870.

Aili D, Enander K, Rydberg J, Nesterenko I, Björefors F, Baltzer L, and Liedberg B: "Folding induced assembly of polypeptide decorated gold nanoparticles.", Journal of the American Chemical Society, 2008, 130:5780-5788.

Enander K, Aili D, Baltzer L, Lundström I, and Liedberg B: "Alpha-helix-inducing dimerization of synthetic polypeptide scaffolds on gold.", Langmuir, 2005, 21:2480-2487.

Enander K, Dolphin G T, and Baltzer L: "Designed, functionalized helix-loop helix motifs that bind human Carbonic Anhydrase II – a new class of synthetic receptor molecules", Journal of the American Chemical Society, 2004, 126:4464-4465.

Enander K, Dolphin G T, Liedberg B, Lundström I, and Baltzer L: "A versatile polypeptide platform for integrated recognition and reporting – affinity arrays for protein-ligand interaction analysis", Chemistry – A European Journal, 2004, 10:2375-2385.

 

PhD thesis

K. Enander, "Folded polypeptide scaffolds for biosensor and biochip applications: design, synthesis, functionalisation and characterisation", Linköping Studies in Science and Technology Dissertation No. 848, 2003.

 

Full publication list